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Extra resources for Allergic Rhinitis

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Mechanisms of IL10 induced T cell inactivation in allergic inflammation and normal response to allergens. Int Arch Allergy Immunol 2001;124:180–182. Allergen Specific Immunotherapy: National Consensus/Working Group for National Consensus. Editor Rajica M. Stosovic: Association of Allergologist and Clinical Immunologist of Serbia and Montenegro 2005; Loznica, Mladost group. Allam JP, Novak N, Fuchs C, Asen S, Berge S, Appel T et al. Characterization of dendritic cells from human oral mucosa: a new Langerhans cell type with high constitutive FC epsilon RI expression.

2002) SLIT was firstly accepted as a viable alternative to SCIT in the World Health Organization (WHO) position paper, published in 1998, and then included in the ARIA guidelines. (Sub-Lingual Immunotherapy World Allergy Organization Position Paper 2009) The main targets for using SLIT are patients of all ages with good correlation between clinical symptoms of allergy and positive allergen specific IgE. Monosenzitized patients are the best candidates for SLIT. Recent studies have investigated using SLIT for the patients with food allergy, latex allergy, atopic dermatitis and allergy on insect venoms.

Faith A, Richards DF, Verhoef A, Lamb JR, Lee TH, Hawrylowicz CM. Impaired secretion of interleukin-4 and interleukin-13 by allergen-specific T cells correlates with defective nuclear expression of NF-AT2 and jun B: relevance to immunotherapy. Clin Exp Allergy 2003;33:1209–1215. Clinical Implications and Facts About Allergic Rhinitis (AR) in Children 29 Fenoglio D, Puppo F, Cirillo I, Vizzaccaro A, Ferrera A, Tosca MA et al. Sublingual specific immunotherapy reduces PBMC proliferations. Eur Ann Allergy Clin Immunol 2005;37:147–151.

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